Imagine More, Create Solutions

Episode 9: Overcoming challenges in protein characterization and innovating with automation (Part 2 with Dr. Edward Kraft, Leash Bio)

In this episode, Dr. Andrew Lee and Dr. Edward Kraft (Leash Bio) chat about the intricacies of high throughput protein characterization. They explore the role of automation in simplifying research processes, discuss various protein characterization methods, and consider the impact of data analytics on the field. Edward Kraft shares his career journey, insights on team management, and thoughts on biotechnology's evolving landscape.

Episode 8: Advances in high throughput protein workflows and automation challenges (Part 1 with Dr. Edward Kraft, Leash Bio)

In this episode, Dr. Andrew Lee and Dr. Edward Kraft (Leash Bio) chat about the intricacies of high throughput protein expression, purification, and characterization. They explore the role of automation in simplifying research processes, discuss various protein expression systems, and consider the merits of different solubility tags and purification techniques. Dr. Kraft shares his career journey, contributions to the field, and thoughts on the biotech industry's evolving landscape. 

Episode 7: Navigating the complexities of lab automation (with Dr. Mike Mueller, Nucleus Automation Partners)

In this episode, Dr. Andrew Lee and Dr. Mike Mueller (Nucleus Automation Partners) talk about automated liquid handlers, particularly TECAN systems. Mike discusses his background, experiences with lab automation, troubleshooting, and programming liquid handlers for specialized applications like size exclusion and affinity chromatography. They also emphasize the importance of creative problem-solving and seeking expert guidance for efficient automation processes.

Episode 6: Exploring the role of agarose resins in biomolecule purification (with Dr. Andy Masters, Purolite)

In this episode, Dr. Andrew Lee and Dr. Andy Masters (Purolite) discuss the role of agarose resins in protein purification and bioprocessing, the benefits of Purolite's jetted technology, how IMCStips utilizes Purolite resins, and Andy Masters’ career journey. They also discuss various aspects of resin technology, including high-throughput screening, the impact of bead size on purification processes, and Purolite's commitment to sustainability and supply security.

Episode 5: Biomolecule purification, advances in chromatography, and automating lab workflows with robotic liquid handlers (with Dr. Patrick Kates and Dr. Todd Mullis, IMCS)

In this episode, Dr. Andrew Lee sits down with IMCS scientists Dr. Patrick Kates and Dr. Todd Mullis to delve into biomolecule purification. They tackle the challenges and advantages of tip-based technologies and discuss automating lab workflows, with a focus on affinity purification and buffer exchange. Tune in for an in-depth look at the technicalities of protein purification and lab automation.

Episode 4: Building a high-performing toxicology lab from the ground up with Michelle Spruill (Sagis)

In this episode, Andrew and Claire chat with Michelle Spruill (Sagis) about the challenges in establishing a toxicology lab and how high-quality reagents like IMCSzyme RT boost low-level drug detection in urine tests. They also cover enzyme kinetics and how buffers enable complete hydrolysis of samples for confirmation testing. Join in to learn about the behind-the-scenes complexities of running a diagnostic lab and how experts like Michelle Spruill navigated these challenges!

Episode 3: Next-generation beta-glucuronidases, modernizing lab workflows and more with Michael Twilbeck (Kokua Analytical Consultants)

Andrew, Claire, and Michael Twilbeck (Kokua Analytical Consultants) delve into the evolution of beta-glucuronidases, detailing how these novel enzymes can optimize laboratory productivity. In addition, they address important issues such as cost assessments, integration complexities, and industry shifts, as well as the benefits of community and collaboration in this field.

Episode 2: The interplay of quality reagents, lab results, and patient care (Part 2 with Dr. Scott Kephart, Quasar Instruments)

Dive back in with Dr. Andrew Lee, Claire Collins, and Quasar's Dr. Scott Kephart in Part 2. In Part 1, we focused on the critical role of quality reagents and validations. Part 2 sheds light on the real-world consequences of subpar lab results, especially for smaller labs. Dive into the intricacies of enzyme hydrolysis with us and see why ensuring quality directly impacts patient care.

Episode 1: Investing in high-quality reagents and stress-testing validations (Part 1 with Dr. Scott Kephart, Quasar Instruments)

In this episode, Dr. Andrew Lee and Claire Collins sit down with Dr. Scott Kephart of Quasar Instruments for a deep dive into the importance of investing in and selecting the right reagents. They discuss factors that affect turnaround times, instrument downtime, and overall laboratory ROI. You see, it's more than data at stake – ultimately, it's about the patients.

IMCS Podcast Trailer

Welcome to our podcast, "Imagine More, Create Solutions," hosted by IMCS co-founder and Chief Scientific Officer Dr. Andrew Lee.